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George Georgiou
Lablog4-68：Mechanistic conformational and substrate selectivity profiles emerging in the evolution of enzymes via parallel trajectories
Authors Christos S Karamitros, Kyle Murray, Yoichi Kumada, Kenneth A Johnson, Sheena D’Arcy, George Georgiou F […] -
George Georgiou
Lablog4-63：Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme
Authors John Blazeck, Christos S. Karamitros, Kyle Ford, Catrina Somody, Ahlam Qerqez, Kyle Murray, Nathaniel […] -
George Georgiou
Lablog4-54：Conformational Dynamics Contribute to Substrate Selectivity and Catalysis in Human Kynureninase
Authors Christos S Karamitros, Kyle Murray, Yusuke Sugiyama, Yoichi Kumada, Kenneth A Johnson, George Georgiou […] -
George Georgiou
Lablog4-52：Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme.
Authors Todd A Triplett, Kendra C Garrison, Nicholas Marshall, Moses Donkor, John Blazeck, Candice Lamb, Ahlam […]
